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Titration

I just started tirzepatide — now what?

Your first weeks on tirzepatide, in plain language — what to expect, what to track, and how to keep all of it private.

Lirea Team

You filled the prescription, took your first dose, and now you’re wondering what the next few months actually look like. Here’s the short version — and the few things worth keeping a record of from day one.

You’re starting low on purpose

Tirzepatide — whether you have it as Mounjaro, Zepbound, or a compounded version — almost always starts at a low dose and steps up over months. That first dose isn’t meant to be your “working” dose; it’s there to let your body adjust. Knowing that up front takes the pressure off week one.

What’s worth tracking

A handful of things tell the real story of how you’re doing:

  • Your shot day. Pick one and keep it. Logging the dose the moment you take it ends the weekly “did I or didn’t I?” question.
  • What dose you’re on, and for how long. When you step up, note it — side effects and appetite often shift with each increase.
  • How you’re feeling. Nausea, fullness, energy. A quick note next to your dose timing turns vague impressions into a pattern you can see.
  • Your weight, as a trend. Not daily noise — the line over weeks.

Go easy on the first weeks

Most early side effects are your body adjusting, and they tend to settle. Eating a little less and a little slower helps. If something feels wrong, that’s a conversation for your prescriber, not the internet.

Keep the record yours

Everything above is sensitive — your dose, your weight, your source. With Lirea it stays encrypted on your phone, with no account and nothing on anyone’s server.

The first month is about settling in, not chasing the scale.

Set your shot day, log as you go, and let the trend show you what’s working.


Your shot. Your data. Your device.

Launching soon

Your shot. Your data. Your device.

Track your weekly dose, your titration, and how you’re feeling — all on your device. No account required. Be first to know when Lirea is live.

One email at launch. No spam, unsubscribe anytime. This list is separate from the app — your health data always stays on your device. Privacy.

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